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Slorth
POLE - LYN
H. sapiens
SSL interaction
Identifiers
Gene Name
Gene ID
Diseases
Drugs
GO terms
Orthologs
POLE
ENSG00000177084
colorectal carcinoma
endometrioid carcinoma
stomach carcinoma
skin cancer
colorectal cancer susceptibility
CLOFARABINE
CYTARABINE
FLUDARABINE PHOSPHATE
GEMCITABINE
nucleotide binding
DNA binding
chromatin binding
DNA-directed DNA polymerase activity
zinc ion binding
single-stranded DNA 3'-5' exodeoxyribonuclease activity
4 iron, 4 sulfur cluster binding
POL2 (S. cerevisiae)
pole-1 (C. elegans)
DNApol-epsilon255 (D. melanogaster)
LYN
ENSG00000254087
No diseases in record
BOSUTINIB
DASATINIB
PONATINIB
protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
signal transducer, downstream of receptor, with protein tyrosine kinase activity
receptor binding
platelet-derived growth factor receptor binding
integrin binding
protein binding
ATP binding
SH3 domain binding
ubiquitin protein ligase binding
gamma-tubulin binding
glycosphingolipid binding
ion channel binding
phosphoprotein binding
Src64B (D. melanogaster)