SMAD2 - FLNA

H. sapiens

SSL interaction

Identifiers

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
SMAD2	ENSG00000175387	colorectal carcinoma hepatocellular carcinoma	No drugs in record	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding chromatin binding double-stranded DNA binding transcription factor activity, sequence-specific DNA binding transforming growth factor beta receptor binding protein binding transcription factor binding phosphatase binding transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity ubiquitin protein ligase binding activating transcription factor binding type I transforming growth factor beta receptor binding enhancer binding protein homodimerization activity SMAD binding metal ion binding protein heterodimerization activity co-SMAD binding I-SMAD binding R-SMAD binding DNA binding	sma-3 (C. elegans) sma-2 (C. elegans)
FLNA	ENSG00000196924	phyllodes tumour of the breast	No drugs in record	G-protein coupled receptor binding glycoprotein binding signal transducer activity protein binding transcription factor binding potassium channel regulator activity Rho GTPase binding Ral GTPase binding kinase binding small GTPase binding mu-type opioid receptor binding Fc-gamma receptor I complex binding protein homodimerization activity ion channel binding SMAD binding Rac GTPase binding actin filament binding GTPase binding cadherin binding involved in cell-cell adhesion	No GO terms in record