CBX5 - WRN

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
CBX5	ENSG00000094916	No diseases in record	No drugs in record	chromatin binding protein binding protein binding, bridging methylated histone binding protein homodimerization activity histone deacetylase binding repressing transcription factor binding	Su(var)205 (D. melanogaster) HP1c (D. melanogaster)
WRN	ENSG00000165392	osteosarcoma meningioma other tumour types	No drugs in record	magnesium ion binding Y-form DNA binding bubble DNA binding DNA binding DNA helicase activity chromatin binding ATP-dependent DNA helicase activity helicase activity exonuclease activity protein binding ATP binding 3'-5' exonuclease activity four-way junction helicase activity ATPase activity manganese ion binding protein complex binding protein homodimerization activity 3'-5' DNA helicase activity ATP-dependent 3'-5' DNA helicase activity G-quadruplex DNA binding	SGS1 (S. cerevisiae) wrn-1 (C. elegans)