INO80 - WRN

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
INO80	ENSG00000128908	No diseases in record	No drugs in record	DNA binding DNA helicase activity actin binding protein binding ATP binding ATPase activity alpha-tubulin binding helicase activity hydrolase activity nucleotide binding ATP-dependent 3'-5' DNA helicase activity regulatory region DNA binding	INO80 (S. cerevisiae) Ino80 (D. melanogaster)
WRN	ENSG00000165392	osteosarcoma meningioma other tumour types	No drugs in record	magnesium ion binding Y-form DNA binding bubble DNA binding DNA binding DNA helicase activity chromatin binding ATP-dependent DNA helicase activity helicase activity exonuclease activity protein binding ATP binding 3'-5' exonuclease activity four-way junction helicase activity ATPase activity manganese ion binding protein complex binding protein homodimerization activity 3'-5' DNA helicase activity ATP-dependent 3'-5' DNA helicase activity G-quadruplex DNA binding	SGS1 (S. cerevisiae) wrn-1 (C. elegans)