TAF11 - WRN

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TAF11	ENSG00000064995	No diseases in record	No drugs in record	DNA binding transcription coactivator activity protein binding vitamin D receptor binding thyroid hormone receptor binding protein heterodimerization activity protein N-terminus binding transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly chromatin binding transcription factor binding transcription factor activity, core RNA polymerase II binding	TAF11 (S. cerevisiae) taf-11.1 (C. elegans) taf-11.3 (C. elegans) taf-11.2 (C. elegans) Taf11 (D. melanogaster)
WRN	ENSG00000165392	osteosarcoma meningioma other tumour types	No drugs in record	magnesium ion binding Y-form DNA binding bubble DNA binding DNA binding DNA helicase activity chromatin binding ATP-dependent DNA helicase activity helicase activity exonuclease activity protein binding ATP binding 3'-5' exonuclease activity four-way junction helicase activity ATPase activity manganese ion binding protein complex binding protein homodimerization activity 3'-5' DNA helicase activity ATP-dependent 3'-5' DNA helicase activity G-quadruplex DNA binding	SGS1 (S. cerevisiae) wrn-1 (C. elegans)