WRN - RUVBL2

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
WRN	ENSG00000165392	osteosarcoma meningioma other tumour types	No drugs in record	magnesium ion binding Y-form DNA binding bubble DNA binding DNA binding DNA helicase activity chromatin binding ATP-dependent DNA helicase activity helicase activity exonuclease activity protein binding ATP binding 3'-5' exonuclease activity four-way junction helicase activity ATPase activity manganese ion binding protein complex binding protein homodimerization activity 3'-5' DNA helicase activity ATP-dependent 3'-5' DNA helicase activity G-quadruplex DNA binding	SGS1 (S. cerevisiae) wrn-1 (C. elegans)
RUVBL2	ENSG00000183207	No diseases in record	No drugs in record	RNA polymerase II core promoter sequence-specific DNA binding RNA polymerase II distal enhancer sequence-specific DNA binding DNA helicase activity ATP-dependent DNA helicase activity protein binding ATP binding chromatin DNA binding identical protein binding ATP-dependent 5'-3' DNA helicase activity unfolded protein binding ATPase activity	RVB2 (S. cerevisiae) rept (D. melanogaster)