CFTR - PMS2

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
CFTR	ENSG00000001626	No diseases in record	CROFELEMER IVACAFTOR LUMACAFTOR	chloride channel activity intracellular ATPase-gated chloride channel activity protein binding ATP binding bicarbonate transmembrane transporter activity chloride transmembrane transporter activity chloride channel regulator activity chloride channel inhibitor activity enzyme binding PDZ domain binding ATPase-coupled anion transmembrane transporter activity	BPT1 (S. cerevisiae)
PMS2	ENSG00000122512	colorectal endometrial ovarian medulloblastoma glioma	No drugs in record	DNA binding endonuclease activity protein binding ATP binding ATPase activity single base insertion or deletion binding single-stranded DNA binding MutSalpha complex binding mismatched DNA binding	PMS1 (S. cerevisiae) Pms2 (D. melanogaster)