PSMB5 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PSMB5	ENSG00000100804	No diseases in record	BORTEZOMIB CARFILZOMIB	threonine-type endopeptidase activity protein binding peptidase activity	PRE2 (S. cerevisiae) Prosbeta5R2 (D. melanogaster) Prosbeta5 (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)