ESR1 - HIP1

H. sapiens

SSL interaction

Identifiers

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
ESR1	ENSG00000091831	breast	BAZEDOXIFENE DIENESTROL DIETHYLSTILBESTROL DIETHYLSTILBESTROL DIPHOSPHATE ENCLOMIPHENE ESTRADIOL ESTRADIOL ACETATE ESTRADIOL CYPIONATE ESTRADIOL VALERATE ESTROGENS, CONJUGATED ESTROGENS, CONJUGATED SYNTHETIC A ESTROGENS, ESTERIFIED ESTRONE ESTRONE SULFURIC ACID ETHINYL ESTRADIOL FULVESTRANT MESTRANOL OSPEMIFENE POLYESTRADIOL PHOSPHATE QUINESTROL RALOXIFENE SYNTHETIC CONJUGATED ESTROGENS, B TAMOXIFEN TOREMIFENE	RNA polymerase II core promoter proximal region sequence-specific DNA binding core promoter sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding chromatin binding transcription factor activity, sequence-specific DNA binding steroid hormone receptor activity steroid binding protein binding beta-catenin binding transcription factor binding zinc ion binding enzyme binding nitric-oxide synthase regulator activity estrogen receptor activity estrogen response element binding RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding identical protein binding ATPase binding	No GO terms in record
HIP1	ENSG00000127946	CMML NSCLC	No drugs in record	epidermal growth factor receptor binding structural constituent of cytoskeleton protein binding clathrin binding clathrin light chain binding phosphatidylinositol-3-phosphate binding phosphatidylinositol binding glutamate receptor binding AP-2 adaptor complex binding clathrin adaptor activity protein homodimerization activity phosphatidylinositol-3,4-bisphosphate binding protein heterodimerization activity actin filament binding phosphatidylinositol-3,5-bisphosphate binding phosphatidylinositol-4,5-bisphosphate binding high-affinity L-histidine transmembrane transporter activity antiporter activity actin binding phospholipid binding transcription corepressor activity	SLA2 (S. cerevisiae) Hip1 (D. melanogaster)