RAD18 - WRN

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
RAD18	ENSG00000070950	No diseases in record	No drugs in record	Y-form DNA binding damaged DNA binding protein binding zinc ion binding ligase activity polyubiquitin binding ubiquitin protein ligase binding protein complex binding identical protein binding single-stranded DNA-dependent ATPase activity ubiquitin protein ligase activity single-stranded DNA binding transferase activity DNA binding metal ion binding	RAD18 (S. cerevisiae)
WRN	ENSG00000165392	osteosarcoma meningioma other tumour types	No drugs in record	magnesium ion binding Y-form DNA binding bubble DNA binding DNA binding DNA helicase activity chromatin binding ATP-dependent DNA helicase activity helicase activity exonuclease activity protein binding ATP binding 3'-5' exonuclease activity four-way junction helicase activity ATPase activity manganese ion binding protein complex binding protein homodimerization activity 3'-5' DNA helicase activity ATP-dependent 3'-5' DNA helicase activity G-quadruplex DNA binding	SGS1 (S. cerevisiae) wrn-1 (C. elegans)