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Slorth
TOP2B - LYN
H. sapiens
SSL interaction
Identifiers
Gene Name
Gene ID
Diseases
Drugs
GO terms
Orthologs
TOP2B
ENSG00000077097
No diseases in record
ETOPOSIDE
TENIPOSIDE
chromatin binding
DNA topoisomerase type II (ATP-hydrolyzing) activity
protein kinase C binding
ATP binding
protein C-terminus binding
DNA binding, bending
enzyme binding
histone deacetylase binding
metal ion binding
protein heterodimerization activity
TOP2 (S. cerevisiae)
cin-4 (C. elegans)
top-2 (C. elegans)
LYN
ENSG00000254087
No diseases in record
BOSUTINIB
DASATINIB
PONATINIB
protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
signal transducer, downstream of receptor, with protein tyrosine kinase activity
receptor binding
platelet-derived growth factor receptor binding
integrin binding
protein binding
ATP binding
SH3 domain binding
ubiquitin protein ligase binding
gamma-tubulin binding
glycosphingolipid binding
ion channel binding
phosphoprotein binding
Src64B (D. melanogaster)