MCM2 - WRN

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
MCM2	ENSG00000073111	No diseases in record	No drugs in record	DNA binding DNA helicase activity DNA replication origin binding protein binding ATP binding enzyme binding histone binding metal ion binding chromatin binding single-stranded DNA-dependent ATP-dependent DNA helicase activity nucleotide binding hydrolase activity helicase activity single-stranded DNA binding 3'-5' DNA helicase activity ATP-dependent DNA helicase activity	MCM2 (S. cerevisiae) Mcm2 (D. melanogaster)
WRN	ENSG00000165392	osteosarcoma meningioma other tumour types	No drugs in record	magnesium ion binding Y-form DNA binding bubble DNA binding DNA binding DNA helicase activity chromatin binding ATP-dependent DNA helicase activity helicase activity exonuclease activity protein binding ATP binding 3'-5' exonuclease activity four-way junction helicase activity ATPase activity manganese ion binding protein complex binding protein homodimerization activity 3'-5' DNA helicase activity ATP-dependent 3'-5' DNA helicase activity G-quadruplex DNA binding	SGS1 (S. cerevisiae) wrn-1 (C. elegans)