TAF6 - SMAD2

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TAF6	ENSG00000106290	No diseases in record	No drugs in record	DNA binding protein binding protein heterodimerization activity transcription factor activity, sequence-specific DNA binding RNA polymerase II activating transcription factor binding protein complex scaffold activity chromatin binding transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly	TAF6 (S. cerevisiae) Taf6 (D. melanogaster)
SMAD2	ENSG00000175387	colorectal carcinoma hepatocellular carcinoma	No drugs in record	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding chromatin binding double-stranded DNA binding transcription factor activity, sequence-specific DNA binding transforming growth factor beta receptor binding protein binding transcription factor binding phosphatase binding transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity ubiquitin protein ligase binding activating transcription factor binding type I transforming growth factor beta receptor binding enhancer binding protein homodimerization activity SMAD binding metal ion binding protein heterodimerization activity co-SMAD binding I-SMAD binding R-SMAD binding DNA binding	sma-3 (C. elegans) sma-2 (C. elegans)