JAK2 - POT1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
JAK2	ENSG00000096968	ALL AML MPN CML	RUXOLITINIB TOFACITINIB	protein kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity receptor binding growth hormone receptor binding interleukin-12 receptor binding protein binding ATP binding protein C-terminus binding protein kinase binding heme binding type 1 angiotensin receptor binding acetylcholine receptor binding histone kinase activity (H3-Y41 specific) SH2 domain binding histone binding phosphatidylinositol 3-kinase binding insulin receptor substrate binding metal ion binding peptide hormone receptor binding	hop (D. melanogaster)
POT1	ENSG00000128513	CLL	No drugs in record	protein binding telomerase inhibitor activity DEAD/H-box RNA helicase binding telomeric DNA binding single-stranded telomeric DNA binding G-rich strand telomeric DNA binding transferase activity acetyl-CoA C-acyltransferase activity mRNA binding transferase activity, transferring acyl groups other than amino-acyl groups transferase activity, transferring acyl groups catalytic activity	No GO terms in record