DLG1 - JAK2

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
DLG1	ENSG00000075711	No diseases in record	No drugs in record	guanylate kinase activity phosphoprotein phosphatase activity protein binding protein C-terminus binding cytoskeletal protein binding ligand-gated ion channel activity potassium channel regulator activity protein kinase binding phosphatase binding mitogen-activated protein kinase kinase binding protein complex scaffold activity ionotropic glutamate receptor binding ion channel binding L27 domain binding cadherin binding involved in cell-cell adhesion structural molecule activity epidermal growth factor receptor binding	GUK1 (S. cerevisiae) dlg1 (D. melanogaster)
JAK2	ENSG00000096968	ALL AML MPN CML	RUXOLITINIB TOFACITINIB	protein kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity receptor binding growth hormone receptor binding interleukin-12 receptor binding protein binding ATP binding protein C-terminus binding protein kinase binding heme binding type 1 angiotensin receptor binding acetylcholine receptor binding histone kinase activity (H3-Y41 specific) SH2 domain binding histone binding phosphatidylinositol 3-kinase binding insulin receptor substrate binding metal ion binding peptide hormone receptor binding	hop (D. melanogaster)