TAF11 - JAK2

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TAF11	ENSG00000064995	No diseases in record	No drugs in record	DNA binding transcription coactivator activity protein binding vitamin D receptor binding thyroid hormone receptor binding protein heterodimerization activity protein N-terminus binding transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly chromatin binding transcription factor binding transcription factor activity, core RNA polymerase II binding	TAF11 (S. cerevisiae) taf-11.1 (C. elegans) taf-11.3 (C. elegans) taf-11.2 (C. elegans) Taf11 (D. melanogaster)
JAK2	ENSG00000096968	ALL AML MPN CML	RUXOLITINIB TOFACITINIB	protein kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity receptor binding growth hormone receptor binding interleukin-12 receptor binding protein binding ATP binding protein C-terminus binding protein kinase binding heme binding type 1 angiotensin receptor binding acetylcholine receptor binding histone kinase activity (H3-Y41 specific) SH2 domain binding histone binding phosphatidylinositol 3-kinase binding insulin receptor substrate binding metal ion binding peptide hormone receptor binding	hop (D. melanogaster)