JAK2 - PARK7

H. sapiens

SSL interaction

Identifiers

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
JAK2	ENSG00000096968	ALL AML MPN CML	RUXOLITINIB TOFACITINIB	protein kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity receptor binding growth hormone receptor binding interleukin-12 receptor binding protein binding ATP binding protein C-terminus binding protein kinase binding heme binding type 1 angiotensin receptor binding acetylcholine receptor binding histone kinase activity (H3-Y41 specific) SH2 domain binding histone binding phosphatidylinositol 3-kinase binding insulin receptor substrate binding metal ion binding peptide hormone receptor binding	hop (D. melanogaster)
PARK7	ENSG00000116288	No diseases in record	No drugs in record	transcription coactivator activity mRNA binding receptor binding copper ion binding protein binding transcription factor binding peptidase activity superoxide dismutase copper chaperone activity oxidoreductase activity, acting on peroxide as acceptor glyoxalase III activity enzyme binding kinase binding cytokine binding tyrosine 3-monooxygenase activator activity L-dopa decarboxylase activator activity protein deglycase activity identical protein binding protein homodimerization activity small protein activating enzyme binding ubiquitin-like protein conjugating enzyme binding mercury ion binding androgen receptor binding peroxiredoxin activity repressing transcription factor binding scaffold protein binding cadherin binding involved in cell-cell adhesion cupric ion binding cuprous ion binding ubiquitin-specific protease binding glyoxalase (glycolic acid-forming) activity core promoter binding double-stranded DNA binding single-stranded DNA binding	DJ-1alpha (D. melanogaster)