JAK2 - FLNA

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
JAK2	ENSG00000096968	ALL AML MPN CML	RUXOLITINIB TOFACITINIB	protein kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity receptor binding growth hormone receptor binding interleukin-12 receptor binding protein binding ATP binding protein C-terminus binding protein kinase binding heme binding type 1 angiotensin receptor binding acetylcholine receptor binding histone kinase activity (H3-Y41 specific) SH2 domain binding histone binding phosphatidylinositol 3-kinase binding insulin receptor substrate binding metal ion binding peptide hormone receptor binding	hop (D. melanogaster)
FLNA	ENSG00000196924	phyllodes tumour of the breast	No drugs in record	G-protein coupled receptor binding glycoprotein binding signal transducer activity protein binding transcription factor binding potassium channel regulator activity Rho GTPase binding Ral GTPase binding kinase binding small GTPase binding mu-type opioid receptor binding Fc-gamma receptor I complex binding protein homodimerization activity ion channel binding SMAD binding Rac GTPase binding actin filament binding GTPase binding cadherin binding involved in cell-cell adhesion	No GO terms in record