JAK2 - NOS3

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
JAK2	ENSG00000096968	ALL AML MPN CML	RUXOLITINIB TOFACITINIB	protein kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity receptor binding growth hormone receptor binding interleukin-12 receptor binding protein binding ATP binding protein C-terminus binding protein kinase binding heme binding type 1 angiotensin receptor binding acetylcholine receptor binding histone kinase activity (H3-Y41 specific) SH2 domain binding histone binding phosphatidylinositol 3-kinase binding insulin receptor substrate binding metal ion binding peptide hormone receptor binding	hop (D. melanogaster)
NOS3	ENSG00000164867	No diseases in record	No drugs in record	actin monomer binding nitric-oxide synthase activity iron ion binding protein binding calmodulin binding FMN binding heme binding tetrahydrobiopterin binding arginine binding cadmium ion binding flavin adenine dinucleotide binding NADP binding scaffold protein binding	NCP1 (S. cerevisiae) nos (D. melanogaster)