JAK2 - DDX5

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
JAK2	ENSG00000096968	ALL AML MPN CML	RUXOLITINIB TOFACITINIB	protein kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity receptor binding growth hormone receptor binding interleukin-12 receptor binding protein binding ATP binding protein C-terminus binding protein kinase binding heme binding type 1 angiotensin receptor binding acetylcholine receptor binding histone kinase activity (H3-Y41 specific) SH2 domain binding histone binding phosphatidylinositol 3-kinase binding insulin receptor substrate binding metal ion binding peptide hormone receptor binding	hop (D. melanogaster)
DDX5	ENSG00000108654	prostate	No drugs in record	transcription coactivator activity RNA helicase activity ATP-dependent RNA helicase activity protein binding calmodulin binding ATP binding enzyme binding estrogen receptor binding pre-mRNA binding calcium-dependent protein binding androgen receptor binding	DBP2 (S. cerevisiae) ddx-17 (C. elegans)