JAK2 - MSN

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
JAK2	ENSG00000096968	ALL AML MPN CML	RUXOLITINIB TOFACITINIB	protein kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity receptor binding growth hormone receptor binding interleukin-12 receptor binding protein binding ATP binding protein C-terminus binding protein kinase binding heme binding type 1 angiotensin receptor binding acetylcholine receptor binding histone kinase activity (H3-Y41 specific) SH2 domain binding histone binding phosphatidylinositol 3-kinase binding insulin receptor substrate binding metal ion binding peptide hormone receptor binding	hop (D. melanogaster)
MSN	ENSG00000147065	ALCL	No drugs in record	double-stranded RNA binding actin binding receptor binding structural constituent of cytoskeleton protein binding protein kinase binding cell adhesion molecule binding MAP kinase kinase kinase kinase activity protein serine/threonine kinase activity signal transducer, downstream of receptor, with serine/threonine kinase activity JUN kinase kinase kinase kinase activity protein kinase activity ATP binding	erm-1 (C. elegans) Moe (D. melanogaster)