JAK2 - TBL1XR1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
JAK2	ENSG00000096968	ALL AML MPN CML	RUXOLITINIB TOFACITINIB	protein kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity receptor binding growth hormone receptor binding interleukin-12 receptor binding protein binding ATP binding protein C-terminus binding protein kinase binding heme binding type 1 angiotensin receptor binding acetylcholine receptor binding histone kinase activity (H3-Y41 specific) SH2 domain binding histone binding phosphatidylinositol 3-kinase binding insulin receptor substrate binding metal ion binding peptide hormone receptor binding	hop (D. melanogaster)
TBL1XR1	ENSG00000177565	splenic marginal zone lymphoma primary central nervous system lymphoma colorectal carcinoma gallbladder carcinoma	No drugs in record	transcription corepressor activity protein binding beta-catenin binding histone binding transcription regulatory region DNA binding protein N-terminus binding	SIF2 (S. cerevisiae) ebi (D. melanogaster)