JAK2 - PPP3CA

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
JAK2	ENSG00000096968	ALL AML MPN CML	RUXOLITINIB TOFACITINIB	protein kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity receptor binding growth hormone receptor binding interleukin-12 receptor binding protein binding ATP binding protein C-terminus binding protein kinase binding heme binding type 1 angiotensin receptor binding acetylcholine receptor binding histone kinase activity (H3-Y41 specific) SH2 domain binding histone binding phosphatidylinositol 3-kinase binding insulin receptor substrate binding metal ion binding peptide hormone receptor binding	hop (D. melanogaster)
PPP3CA	ENSG00000138814	No diseases in record	No drugs in record	protein serine/threonine phosphatase activity calcium ion binding protein binding calmodulin binding drug binding enzyme binding calmodulin-dependent protein phosphatase activity protein heterodimerization activity protein dimerization activity	CMP2 (S. cerevisiae) CNA1 (S. cerevisiae) tax-6 (C. elegans) CanA1 (D. melanogaster) Pp2B-14D (D. melanogaster)