RAD18 - JAK2

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
RAD18	ENSG00000070950	No diseases in record	No drugs in record	Y-form DNA binding damaged DNA binding protein binding zinc ion binding ligase activity polyubiquitin binding ubiquitin protein ligase binding protein complex binding identical protein binding single-stranded DNA-dependent ATPase activity ubiquitin protein ligase activity single-stranded DNA binding transferase activity DNA binding metal ion binding	RAD18 (S. cerevisiae)
JAK2	ENSG00000096968	ALL AML MPN CML	RUXOLITINIB TOFACITINIB	protein kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity receptor binding growth hormone receptor binding interleukin-12 receptor binding protein binding ATP binding protein C-terminus binding protein kinase binding heme binding type 1 angiotensin receptor binding acetylcholine receptor binding histone kinase activity (H3-Y41 specific) SH2 domain binding histone binding phosphatidylinositol 3-kinase binding insulin receptor substrate binding metal ion binding peptide hormone receptor binding	hop (D. melanogaster)