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Slorth
JAK2 - LRRK2
H. sapiens
SSL interaction
Identifiers
Gene Name
Gene ID
Diseases
Drugs
GO terms
Orthologs
JAK2
ENSG00000096968
ALL
AML
MPN
CML
RUXOLITINIB
TOFACITINIB
protein kinase activity
protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
Ras guanyl-nucleotide exchange factor activity
receptor binding
growth hormone receptor binding
interleukin-12 receptor binding
protein binding
ATP binding
protein C-terminus binding
protein kinase binding
heme binding
type 1 angiotensin receptor binding
acetylcholine receptor binding
histone kinase activity (H3-Y41 specific)
SH2 domain binding
histone binding
phosphatidylinositol 3-kinase binding
insulin receptor substrate binding
metal ion binding
peptide hormone receptor binding
hop (D. melanogaster)
LRRK2
ENSG00000188906
No diseases in record
No drugs in record
SNARE binding
glycoprotein binding
actin binding
GTPase activity
protein kinase activity
protein serine/threonine kinase activity
MAP kinase kinase activity
GTPase activator activity
protein binding
ATP binding
GTP binding
microtubule binding
tubulin binding
kinase activity
Rho GTPase binding
syntaxin-1 binding
receptor signaling complex scaffold activity
clathrin binding
GTP-dependent protein kinase activity
peroxidase inhibitor activity
co-receptor binding
identical protein binding
protein homodimerization activity
ion channel binding
protein kinase A binding
beta-catenin destruction complex binding
MEK1 (S. cerevisiae)