HDAC9 - JAK2

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
HDAC9	ENSG00000048052	No diseases in record	BELINOSTAT PANOBINOSTAT ROMIDEPSIN	transcription corepressor activity histone deacetylase activity protein kinase C binding protein binding transcription factor binding NAD-dependent histone deacetylase activity (H3-K14 specific) protein deacetylase activity histone deacetylase binding metal ion binding repressing transcription factor binding	HDA1 (S. cerevisiae) hda-4 (C. elegans) HDAC4 (D. melanogaster)
JAK2	ENSG00000096968	ALL AML MPN CML	RUXOLITINIB TOFACITINIB	protein kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity receptor binding growth hormone receptor binding interleukin-12 receptor binding protein binding ATP binding protein C-terminus binding protein kinase binding heme binding type 1 angiotensin receptor binding acetylcholine receptor binding histone kinase activity (H3-Y41 specific) SH2 domain binding histone binding phosphatidylinositol 3-kinase binding insulin receptor substrate binding metal ion binding peptide hormone receptor binding	hop (D. melanogaster)