RAD51 - JAK2

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
RAD51	ENSG00000051180	No diseases in record	No drugs in record	recombinase activity four-way junction DNA binding chromatin binding double-stranded DNA binding single-stranded DNA binding protein binding ATP binding protein C-terminus binding identical protein binding single-stranded DNA-dependent ATPase activity DNA polymerase binding endodeoxyribonuclease activity DNA-dependent ATPase activity nucleotide binding DNA binding ATPase activity Swi5-Sfr1 complex binding protein-DNA loading ATPase activity	RAD51 (S. cerevisiae) rad-51 (C. elegans) spn-A (D. melanogaster)
JAK2	ENSG00000096968	ALL AML MPN CML	RUXOLITINIB TOFACITINIB	protein kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity receptor binding growth hormone receptor binding interleukin-12 receptor binding protein binding ATP binding protein C-terminus binding protein kinase binding heme binding type 1 angiotensin receptor binding acetylcholine receptor binding histone kinase activity (H3-Y41 specific) SH2 domain binding histone binding phosphatidylinositol 3-kinase binding insulin receptor substrate binding metal ion binding peptide hormone receptor binding	hop (D. melanogaster)