JAK2 - CLP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
JAK2	ENSG00000096968	ALL AML MPN CML	RUXOLITINIB TOFACITINIB	protein kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity receptor binding growth hormone receptor binding interleukin-12 receptor binding protein binding ATP binding protein C-terminus binding protein kinase binding heme binding type 1 angiotensin receptor binding acetylcholine receptor binding histone kinase activity (H3-Y41 specific) SH2 domain binding histone binding phosphatidylinositol 3-kinase binding insulin receptor substrate binding metal ion binding peptide hormone receptor binding	hop (D. melanogaster)
CLP1	ENSG00000172409	AML	No drugs in record	ATP binding ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity polydeoxyribonucleotide kinase activity ATP-dependent polyribonucleotide 5'-hydroxyl-kinase activity RNA binding nucleotide binding polynucleotide 5'-hydroxyl-kinase activity protein serine/threonine phosphatase activity phosphoprotein phosphatase activity protein binding protein tyrosine phosphatase activity	CLP1 (S. cerevisiae) clpf-1 (C. elegans) cbc (D. melanogaster)