JAK2 - CALM1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
JAK2	ENSG00000096968	ALL AML MPN CML	RUXOLITINIB TOFACITINIB	protein kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity receptor binding growth hormone receptor binding interleukin-12 receptor binding protein binding ATP binding protein C-terminus binding protein kinase binding heme binding type 1 angiotensin receptor binding acetylcholine receptor binding histone kinase activity (H3-Y41 specific) SH2 domain binding histone binding phosphatidylinositol 3-kinase binding insulin receptor substrate binding metal ion binding peptide hormone receptor binding	hop (D. melanogaster)
CALM1	ENSG00000198668	No diseases in record	No drugs in record	Ras guanyl-nucleotide exchange factor activity calcium ion binding protein binding inositol-1,4,5-trisphosphate 3-kinase activity ligand-gated ion channel activity protein kinase binding protein domain specific binding titin binding thioesterase binding N-terminal myristoylation domain binding phospholipase binding protein serine/threonine kinase activator activity ion channel binding protein phosphatase activator activity	CMD1 (S. cerevisiae) Cam (D. melanogaster)