DNA2 - SMAD1

H. sapiens

SSL interaction

Identifiers

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
DNA2	ENSG00000138346	No diseases in record	No drugs in record	DNA binding DNA helicase activity helicase activity nuclease activity protein binding ATP binding ATPase activity site-specific endodeoxyribonuclease activity, specific for altered base 5'-flap endonuclease activity 5'-3' DNA helicase activity single-stranded DNA-dependent ATPase activity metal ion binding 4 iron, 4 sulfur cluster binding catalytic activity ATP-dependent DNA helicase activity single-stranded DNA endodeoxyribonuclease activity nucleotide binding hydrolase activity iron-sulfur cluster binding chromatin binding 5' overhang single-stranded DNA endodeoxyribonuclease activity single-stranded DNA 5'-3' exodeoxyribonuclease activity	DNA2 (S. cerevisiae) dna-2 (C. elegans) CG2990 (D. melanogaster)
SMAD1	ENSG00000170365	No diseases in record	No drugs in record	RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II core promoter sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding transcription factor activity, sequence-specific DNA binding signal transducer activity, downstream of receptor protein binding protein kinase binding transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity identical protein binding protein homodimerization activity metal ion binding protein heterodimerization activity co-SMAD binding I-SMAD binding primary miRNA binding	sma-3 (C. elegans) sma-2 (C. elegans)