HDAC2 - SMARCA4

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
HDAC2	ENSG00000196591	No diseases in record	BELINOSTAT PANOBINOSTAT ROMIDEPSIN VORINOSTAT	core promoter binding RNA polymerase II repressing transcription factor binding chromatin binding histone deacetylase activity protein binding transcription factor binding deacetylase activity enzyme binding heat shock protein binding NAD-dependent histone deacetylase activity (H3-K14 specific) protein deacetylase activity sequence-specific DNA binding NF-kappaB binding RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II distal enhancer sequence-specific DNA binding nucleosomal DNA binding	RPD3 (S. cerevisiae) hda-1 (C. elegans) hda-3 (C. elegans)
SMARCA4	ENSG00000127616	NSCLC SCCOHT	No drugs in record	RNA polymerase II transcription coactivator activity RNA polymerase I CORE element sequence-specific DNA binding p53 binding transcription coactivator activity transcription corepressor activity helicase activity protein binding ATP binding DNA-dependent ATPase activity transcription factor binding Tat protein binding protein N-terminus binding androgen receptor binding DNA polymerase binding lysine-acetylated histone binding RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II distal enhancer sequence-specific DNA binding nucleosomal DNA binding	STH1 (S. cerevisiae) swsn-4 (C. elegans) brm (D. melanogaster)