PDPK1 - LCK

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PDPK1	ENSG00000140992	No diseases in record	No drugs in record	protein serine/threonine kinase activity 3-phosphoinositide-dependent protein kinase activity insulin receptor binding protein binding ATP binding phospholipase activator activity kinase activity protein kinase binding phospholipase binding	PKH1 (S. cerevisiae) PKH2 (S. cerevisiae) pdk-1 (C. elegans) Pdk1 (D. melanogaster)
LCK	ENSG00000182866	T-ALL	DASATINIB PAZOPANIB	glycoprotein binding protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity protein serine/threonine phosphatase activity protein binding ATP binding protein C-terminus binding kinase activity protein kinase binding protein phosphatase binding SH2 domain binding CD4 receptor binding CD8 receptor binding identical protein binding phosphatidylinositol 3-kinase binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity ATPase binding	Src64B (D. melanogaster)