CUL3 - JAK3

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
CUL3	ENSG00000036257	lung cancer	No drugs in record	protein binding cyclin binding POZ domain binding ubiquitin protein ligase binding protein homodimerization activity protein heterodimerization activity ubiquitin-protein transferase activity ubiquitin protein ligase activity	CDC53 (S. cerevisiae) Cul3 (D. melanogaster)
JAK3	ENSG00000105639	acute megakaryocytic leukaemia ETP ALL	TOFACITINIB	protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity receptor binding protein binding ATP binding protein phosphatase binding	hop (D. melanogaster)