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FH - TOP2A
H. sapiens
SSL interaction
Identifiers
Gene Name
Gene ID
Diseases
Drugs
GO terms
Orthologs
FH
ENSG00000091483
leiomyomatosis
renal
No drugs in record
fumarate hydratase activity
protein binding
iron chaperone activity
ferrous iron binding
ferroxidase activity
2 iron, 2 sulfur cluster binding
ferric iron binding
FUM1 (S. cerevisiae)
fum-1 (C. elegans)
TOP2A
ENSG00000131747
No diseases in record
DAUNORUBICIN
DOXORUBICIN
EPIRUBICIN
ETOPOSIDE
ETOPOSIDE PHOSPHATE
IDARUBICIN
MITOXANTRONE
PODOFILOX
TENIPOSIDE
VALRUBICIN
magnesium ion binding
DNA binding
chromatin binding
DNA topoisomerase type II (ATP-hydrolyzing) activity
protein kinase C binding
protein binding
ATP binding
protein C-terminus binding
DNA-dependent ATPase activity
drug binding
DNA binding, bending
enzyme binding
protein homodimerization activity
histone deacetylase binding
ubiquitin binding
protein heterodimerization activity
TOP2 (S. cerevisiae)
cin-4 (C. elegans)
top-2 (C. elegans)
References
2342133