FH - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
FH	ENSG00000091483	leiomyomatosis renal	No drugs in record	fumarate hydratase activity protein binding iron chaperone activity ferrous iron binding ferroxidase activity 2 iron, 2 sulfur cluster binding ferric iron binding	FUM1 (S. cerevisiae) fum-1 (C. elegans)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)