MAP2K4 - APEX1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
MAP2K4	ENSG00000065559	pancreatic breast colorectal	No drugs in record	protein kinase activity signal transducer, downstream of receptor, with serine/threonine kinase activity protein tyrosine kinase activity protein binding ATP binding JUN kinase kinase activity mitogen-activated protein kinase kinase kinase binding	PBS2 (S. cerevisiae) sek-3 (C. elegans) mkk-4 (C. elegans) sek-6 (C. elegans) Mkk4 (D. melanogaster)
APEX1	ENSG00000100823	No diseases in record	No drugs in record	DNA binding damaged DNA binding double-stranded telomeric DNA binding transcription coactivator activity transcription corepressor activity DNA-(apurinic or apyrimidinic site) lyase activity endonuclease activity endodeoxyribonuclease activity RNA-DNA hybrid ribonuclease activity phosphodiesterase I activity uracil DNA N-glycosylase activity protein binding phosphoric diester hydrolase activity double-stranded DNA exodeoxyribonuclease activity double-stranded DNA 3'-5' exodeoxyribonuclease activity 3'-5' exonuclease activity oxidoreductase activity site-specific endodeoxyribonuclease activity, specific for altered base chromatin DNA binding protein complex binding metal ion binding NF-kappaB binding	APN2 (S. cerevisiae) exo-3 (C. elegans) Rrp1 (D. melanogaster)