Home
Interactions
Genes
Downloads
Contact
Slorth
TSC2 - TOP2A
H. sapiens
SSL interaction
Identifiers
Gene Name
Gene ID
Diseases
Drugs
GO terms
Orthologs
TSC2
ENSG00000103197
pulmonary lymphangioleiomyomatosis
renal angiomyolipoma
HNSCC
hamartoma
renal cell carcinoma
tuberous sclerosis tuber
No drugs in record
GTPase activator activity
protein binding
phosphatase binding
small GTPase binding
protein homodimerization activity
No GO terms in record
TOP2A
ENSG00000131747
No diseases in record
DAUNORUBICIN
DOXORUBICIN
EPIRUBICIN
ETOPOSIDE
ETOPOSIDE PHOSPHATE
IDARUBICIN
MITOXANTRONE
PODOFILOX
TENIPOSIDE
VALRUBICIN
magnesium ion binding
DNA binding
chromatin binding
DNA topoisomerase type II (ATP-hydrolyzing) activity
protein kinase C binding
protein binding
ATP binding
protein C-terminus binding
DNA-dependent ATPase activity
drug binding
DNA binding, bending
enzyme binding
protein homodimerization activity
histone deacetylase binding
ubiquitin binding
protein heterodimerization activity
TOP2 (S. cerevisiae)
cin-4 (C. elegans)
top-2 (C. elegans)