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TNFAIP3 - TOP2A
H. sapiens
SSL interaction
Identifiers
Gene Name
Gene ID
Diseases
Drugs
GO terms
Orthologs
TNFAIP3
ENSG00000118503
marginal zone B-cell lymphomas
Hodgkin lymphoma
PMBL
No drugs in record
protease binding
DNA binding
ubiquitin-protein transferase activity
thiol-dependent ubiquitin-specific protease activity
protein binding
zinc ion binding
ligase activity
kinase binding
identical protein binding
ubiquitin binding
protein self-association
K63-linked polyubiquitin binding
No GO terms in record
TOP2A
ENSG00000131747
No diseases in record
DAUNORUBICIN
DOXORUBICIN
EPIRUBICIN
ETOPOSIDE
ETOPOSIDE PHOSPHATE
IDARUBICIN
MITOXANTRONE
PODOFILOX
TENIPOSIDE
VALRUBICIN
magnesium ion binding
DNA binding
chromatin binding
DNA topoisomerase type II (ATP-hydrolyzing) activity
protein kinase C binding
protein binding
ATP binding
protein C-terminus binding
DNA-dependent ATPase activity
drug binding
DNA binding, bending
enzyme binding
protein homodimerization activity
histone deacetylase binding
ubiquitin binding
protein heterodimerization activity
TOP2 (S. cerevisiae)
cin-4 (C. elegans)
top-2 (C. elegans)