BIRC5 - TOP2A

H. sapiens

SSL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
BIRC5 ENSG00000089685

No diseases in record

No drugs in record

ubiquitin-protein transferase activity
cysteine-type endopeptidase inhibitor activity
protein binding
microtubule binding
Ran GTPase binding
enzyme binding
identical protein binding
metal ion binding
chaperone binding

No GO terms in record

TOP2A ENSG00000131747

No diseases in record

DAUNORUBICIN
DOXORUBICIN
EPIRUBICIN
ETOPOSIDE
ETOPOSIDE PHOSPHATE
IDARUBICIN
MITOXANTRONE
PODOFILOX
TENIPOSIDE
VALRUBICIN
magnesium ion binding
DNA binding
chromatin binding
DNA topoisomerase type II (ATP-hydrolyzing) activity
protein kinase C binding
protein binding
ATP binding
protein C-terminus binding
DNA-dependent ATPase activity
drug binding
DNA binding, bending
enzyme binding
protein homodimerization activity
histone deacetylase binding
ubiquitin binding
protein heterodimerization activity
TOP2 (S. cerevisiae)
cin-4 (C. elegans)
top-2 (C. elegans)