TCF3 - TOP2A

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TCF3	ENSG00000071564	pre B-ALL	No drugs in record	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding DNA binding transcription factor activity, sequence-specific DNA binding transcription coactivator activity protein binding transcription factor binding mitogen-activated protein kinase kinase kinase binding enhancer binding protein homodimerization activity bHLH transcription factor binding protein heterodimerization activity repressing transcription factor binding vitamin D response element binding E-box binding	hlh-2 (C. elegans)
TOP2A	ENSG00000131747	No diseases in record	DAUNORUBICIN DOXORUBICIN EPIRUBICIN ETOPOSIDE ETOPOSIDE PHOSPHATE IDARUBICIN MITOXANTRONE PODOFILOX TENIPOSIDE VALRUBICIN	magnesium ion binding DNA binding chromatin binding DNA topoisomerase type II (ATP-hydrolyzing) activity protein kinase C binding protein binding ATP binding protein C-terminus binding DNA-dependent ATPase activity drug binding DNA binding, bending enzyme binding protein homodimerization activity histone deacetylase binding ubiquitin binding protein heterodimerization activity	TOP2 (S. cerevisiae) cin-4 (C. elegans) top-2 (C. elegans)