RAD1 - TOP2A

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
RAD1	ENSG00000113456	No diseases in record	No drugs in record	damaged DNA binding protein binding 3'-5' exonuclease activity exodeoxyribonuclease III activity DNA binding nuclease activity single-stranded DNA binding endodeoxyribonuclease activity hydrolase activity endonuclease activity single-stranded DNA endodeoxyribonuclease activity	mrt-2 (C. elegans) Rad1 (D. melanogaster)
TOP2A	ENSG00000131747	No diseases in record	DAUNORUBICIN DOXORUBICIN EPIRUBICIN ETOPOSIDE ETOPOSIDE PHOSPHATE IDARUBICIN MITOXANTRONE PODOFILOX TENIPOSIDE VALRUBICIN	magnesium ion binding DNA binding chromatin binding DNA topoisomerase type II (ATP-hydrolyzing) activity protein kinase C binding protein binding ATP binding protein C-terminus binding DNA-dependent ATPase activity drug binding DNA binding, bending enzyme binding protein homodimerization activity histone deacetylase binding ubiquitin binding protein heterodimerization activity	TOP2 (S. cerevisiae) cin-4 (C. elegans) top-2 (C. elegans)