RAD18 - TOP2A

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
RAD18	ENSG00000070950	No diseases in record	No drugs in record	Y-form DNA binding damaged DNA binding protein binding zinc ion binding ligase activity polyubiquitin binding ubiquitin protein ligase binding protein complex binding identical protein binding single-stranded DNA-dependent ATPase activity ubiquitin protein ligase activity single-stranded DNA binding transferase activity DNA binding metal ion binding	RAD18 (S. cerevisiae)
TOP2A	ENSG00000131747	No diseases in record	DAUNORUBICIN DOXORUBICIN EPIRUBICIN ETOPOSIDE ETOPOSIDE PHOSPHATE IDARUBICIN MITOXANTRONE PODOFILOX TENIPOSIDE VALRUBICIN	magnesium ion binding DNA binding chromatin binding DNA topoisomerase type II (ATP-hydrolyzing) activity protein kinase C binding protein binding ATP binding protein C-terminus binding DNA-dependent ATPase activity drug binding DNA binding, bending enzyme binding protein homodimerization activity histone deacetylase binding ubiquitin binding protein heterodimerization activity	TOP2 (S. cerevisiae) cin-4 (C. elegans) top-2 (C. elegans)