DDX1 - TOP2A

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
DDX1	ENSG00000079785	No diseases in record	No drugs in record	DNA binding chromatin binding transcription cofactor activity RNA helicase activity double-stranded RNA binding ATP-dependent RNA helicase activity nuclease activity exonuclease activity protein binding ATP binding ATP-dependent helicase activity poly(A) binding DNA/RNA helicase activity helicase activity	DBP3 (S. cerevisiae) MSS116 (S. cerevisiae) Y55F3BR.1 (C. elegans) Ddx1 (D. melanogaster)
TOP2A	ENSG00000131747	No diseases in record	DAUNORUBICIN DOXORUBICIN EPIRUBICIN ETOPOSIDE ETOPOSIDE PHOSPHATE IDARUBICIN MITOXANTRONE PODOFILOX TENIPOSIDE VALRUBICIN	magnesium ion binding DNA binding chromatin binding DNA topoisomerase type II (ATP-hydrolyzing) activity protein kinase C binding protein binding ATP binding protein C-terminus binding DNA-dependent ATPase activity drug binding DNA binding, bending enzyme binding protein homodimerization activity histone deacetylase binding ubiquitin binding protein heterodimerization activity	TOP2 (S. cerevisiae) cin-4 (C. elegans) top-2 (C. elegans)