TOP2A - SYVN1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TOP2A	ENSG00000131747	No diseases in record	DAUNORUBICIN DOXORUBICIN EPIRUBICIN ETOPOSIDE ETOPOSIDE PHOSPHATE IDARUBICIN MITOXANTRONE PODOFILOX TENIPOSIDE VALRUBICIN	magnesium ion binding DNA binding chromatin binding DNA topoisomerase type II (ATP-hydrolyzing) activity protein kinase C binding protein binding ATP binding protein C-terminus binding DNA-dependent ATPase activity drug binding DNA binding, bending enzyme binding protein homodimerization activity histone deacetylase binding ubiquitin binding protein heterodimerization activity	TOP2 (S. cerevisiae) cin-4 (C. elegans) top-2 (C. elegans)
SYVN1	ENSG00000162298	No diseases in record	No drugs in record	protein binding zinc ion binding ligase activity unfolded protein binding chaperone binding ATPase binding ubiquitin protein ligase activity ubiquitin protein ligase activity involved in ERAD pathway ubiquitin-specific protease binding	HRD1 (S. cerevisiae) sip3 (D. melanogaster)