RAD51 - TOP2A

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
RAD51	ENSG00000051180	No diseases in record	No drugs in record	recombinase activity four-way junction DNA binding chromatin binding double-stranded DNA binding single-stranded DNA binding protein binding ATP binding protein C-terminus binding identical protein binding single-stranded DNA-dependent ATPase activity DNA polymerase binding endodeoxyribonuclease activity DNA-dependent ATPase activity nucleotide binding DNA binding ATPase activity Swi5-Sfr1 complex binding protein-DNA loading ATPase activity	RAD51 (S. cerevisiae) rad-51 (C. elegans) spn-A (D. melanogaster)
TOP2A	ENSG00000131747	No diseases in record	DAUNORUBICIN DOXORUBICIN EPIRUBICIN ETOPOSIDE ETOPOSIDE PHOSPHATE IDARUBICIN MITOXANTRONE PODOFILOX TENIPOSIDE VALRUBICIN	magnesium ion binding DNA binding chromatin binding DNA topoisomerase type II (ATP-hydrolyzing) activity protein kinase C binding protein binding ATP binding protein C-terminus binding DNA-dependent ATPase activity drug binding DNA binding, bending enzyme binding protein homodimerization activity histone deacetylase binding ubiquitin binding protein heterodimerization activity	TOP2 (S. cerevisiae) cin-4 (C. elegans) top-2 (C. elegans)