PLCG1 - MAP2K2

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PLCG1	ENSG00000124181	angiosarcoma	No drugs in record	phosphatidylinositol phospholipase C activity phospholipase C activity signal transducer activity, downstream of receptor neurotrophin TRKA receptor binding calcium ion binding protein binding protein kinase binding receptor tyrosine kinase binding glutamate receptor binding	PLC1 (S. cerevisiae) plc-3 (C. elegans) sl (D. melanogaster)
MAP2K2	ENSG00000126934	NSCLC melanoma	TRAMETINIB	protein serine/threonine kinase activity signal transducer, downstream of receptor, with serine/threonine kinase activity MAP kinase kinase activity protein serine/threonine/tyrosine kinase activity protein tyrosine kinase activity protein binding ATP binding PDZ domain binding protein serine/threonine kinase activator activity metal ion binding scaffold protein binding	PBS2 (S. cerevisiae) mek-2 (C. elegans) Dsor1 (D. melanogaster)