CUL3 - MAP2K2

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
CUL3	ENSG00000036257	lung cancer	No drugs in record	protein binding cyclin binding POZ domain binding ubiquitin protein ligase binding protein homodimerization activity protein heterodimerization activity ubiquitin-protein transferase activity ubiquitin protein ligase activity	CDC53 (S. cerevisiae) Cul3 (D. melanogaster)
MAP2K2	ENSG00000126934	NSCLC melanoma	TRAMETINIB	protein serine/threonine kinase activity signal transducer, downstream of receptor, with serine/threonine kinase activity MAP kinase kinase activity protein serine/threonine/tyrosine kinase activity protein tyrosine kinase activity protein binding ATP binding PDZ domain binding protein serine/threonine kinase activator activity metal ion binding scaffold protein binding	PBS2 (S. cerevisiae) mek-2 (C. elegans) Dsor1 (D. melanogaster)