SGK1 - LCK

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
SGK1	ENSG00000118515	Nodular lymphocyte predominant Hodgkin lymphoma	No drugs in record	protein serine/threonine kinase activity protein serine/threonine/tyrosine kinase activity calcium channel regulator activity protein binding ATP binding potassium channel regulator activity sodium channel regulator activity chloride channel regulator activity	SCH9 (S. cerevisiae) YPK1 (S. cerevisiae) YPK2 (S. cerevisiae) sgk-1 (C. elegans)
LCK	ENSG00000182866	T-ALL	DASATINIB PAZOPANIB	glycoprotein binding protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity protein serine/threonine phosphatase activity protein binding ATP binding protein C-terminus binding kinase activity protein kinase binding protein phosphatase binding SH2 domain binding CD4 receptor binding CD8 receptor binding identical protein binding phosphatidylinositol 3-kinase binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity ATPase binding	Src64B (D. melanogaster)