TCF7L2 - FEN1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TCF7L2	ENSG00000148737	colorectal	No drugs in record	RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II repressing transcription factor binding transcription factor activity, sequence-specific DNA binding protein binding beta-catenin binding transcription factor binding protein kinase binding nuclear hormone receptor binding sequence-specific DNA binding transcription regulatory region DNA binding gamma-catenin binding armadillo repeat domain binding	pop-1 (C. elegans) pan (D. melanogaster)
FEN1	ENSG00000168496	breast cancer	No drugs in record	magnesium ion binding DNA binding damaged DNA binding double-stranded DNA binding endonuclease activity RNA-DNA hybrid ribonuclease activity exonuclease activity protein binding double-stranded DNA exodeoxyribonuclease activity 5'-3' exonuclease activity 5'-flap endonuclease activity flap endonuclease activity nuclease activity	RAD27 (S. cerevisiae) crn-1 (C. elegans)