MCM4 - TOP2A

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
MCM4	ENSG00000104738	No diseases in record	No drugs in record	single-stranded DNA binding protein binding ATP binding ATP-dependent DNA helicase activity single-stranded DNA-dependent ATP-dependent DNA helicase activity ATP-dependent four-way junction helicase activity DNA replication origin binding DNA binding helicase activity ATP-dependent 3'-5' DNA helicase activity DNA helicase activity nucleotide binding single-stranded DNA-dependent ATPase activity hydrolase activity single-stranded RNA binding 3'-5' DNA/RNA helicase activity ATPase activity single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity RNA helicase activity chromatin binding	MCM4 (S. cerevisiae) dpa (D. melanogaster)
TOP2A	ENSG00000131747	No diseases in record	DAUNORUBICIN DOXORUBICIN EPIRUBICIN ETOPOSIDE ETOPOSIDE PHOSPHATE IDARUBICIN MITOXANTRONE PODOFILOX TENIPOSIDE VALRUBICIN	magnesium ion binding DNA binding chromatin binding DNA topoisomerase type II (ATP-hydrolyzing) activity protein kinase C binding protein binding ATP binding protein C-terminus binding DNA-dependent ATPase activity drug binding DNA binding, bending enzyme binding protein homodimerization activity histone deacetylase binding ubiquitin binding protein heterodimerization activity	TOP2 (S. cerevisiae) cin-4 (C. elegans) top-2 (C. elegans)